Slator R, Goodacre T E
Department of Plastic and Reconstructive Surgery, Radcliffe Infirmary, Oxford, UK.
Br J Plast Surg. 1995 Apr;48(3):150-3. doi: 10.1016/0007-1226(95)90146-9.
A prospective, randomised, double blind trial was carried out to test whether or not the application of topical anaesthetic cream (EMLA cream) before infiltration of local anaesthetic would decrease the discomfort of correction of prominent ears under local anaesthetic. 23 patients were entered into the trial. They acted as their own controls, one ear having EMLA cream applied approximately 2 h prior to surgery, and the other Aqueous cream. Immediately after surgery, the patients were asked to complete two scales describing the amount of pain they had felt in each ear, both at the time of injection of local anaesthetic and during the surgery. They were also asked whether they thought the inconvenience associated with the use of the EMLA cream was worth any improvement they felt. The results showed that, compared to the placebo cream, EMLA cream significantly decreased the pain felt both at the time of injection (p < 0.005) and during the surgery (p < 0.01). However, only 62% of patients asked felt that the inconvenience associated with the use of EMLA cream was worth the benefits that it conveyed.
开展了一项前瞻性、随机、双盲试验，以测试在局部麻醉剂浸润前涂抹局部麻醉乳膏（EMLA乳膏）是否会减轻局部麻醉下矫正招风耳的不适感。23名患者参与了该试验。他们自身作为对照，一只耳朵在手术前约2小时涂抹EMLA乳膏，另一只耳朵涂抹水性乳膏。手术后，立即要求患者完成两个量表，描述他们在每只耳朵注射局部麻醉剂时和手术期间所感受到的疼痛程度。还询问他们是否认为使用EMLA乳膏带来的不便与他们感受到的任何改善是值得的。结果显示，与安慰剂乳膏相比，EMLA乳膏在注射时（p < 0.005）和手术期间（p < 0.01）均显著减轻了疼痛。然而，只有62%的受访患者认为使用EMLA乳膏带来的不便与它所带来的益处是值得的。
