Baumann P C, Harshbarger J C
LSC Field Research Station, Ohio State University, Columbus 43210, USA.
Environ Health Perspect. 1995 Feb;103(2):168-70. doi: 10.1289/ehp.95103168.
Polycyclic aromatic hydrocarbons (PAHs) in both sediment and brown bullhead catfish tissues from the Black River in Lorain County, Ohio, declined by 65% and 93%, respectively, between 1980 and 1982. Sediment PAHs declined an additional 99% by 1987, coincident with the closure of a coking facility in 1983. Contemporaneously, liver cancer in 3- to 4-year-old brown bullheads declined to about one-quarter the 1982 frequency (10% versus 39%) by 1987, while the percentage of livers without any proliferative lesions doubled (42% versus 20%). These changes were significant within age group. Our data affirm a cause-and-effect relationship between PAH exposure and liver cancer in wild fish. The data also support the efficacy of natural, unassisted remediation once the source of the pollution is eliminated.
1980年至1982年间，俄亥俄州洛雷恩县黑河沉积物和褐首鲶鱼组织中的多环芳烃（PAHs）分别下降了65%和93%。到1987年，沉积物中的PAHs又下降了99%，这与1983年一家炼焦厂的关闭同时发生。与此同时，3至4岁褐首鲶鱼的肝癌发病率到1987年降至1982年发病率的约四分之一（10%对39%），而没有任何增殖性病变的肝脏比例翻了一番（42%对20%）。这些变化在同一年龄组内具有显著性。我们的数据证实了野生鱼类接触PAHs与肝癌之间的因果关系。数据还支持一旦消除污染源，自然、无辅助修复的有效性。
