焦化厂关闭且环境中多环芳烃含量大幅下降后，野生褐首鲶肝脏肿瘤数量减少。
Decline in liver neoplasms in wild brown bullhead catfish after coking plant closes and environmental PAHs plummet.
作者信息
Baumann P C, Harshbarger J C
机构信息
LSC Field Research Station, Ohio State University, Columbus 43210, USA.
出版信息
Environ Health Perspect. 1995 Feb;103(2):168-70. doi: 10.1289/ehp.95103168.
Abstract
Polycyclic aromatic hydrocarbons (PAHs) in both sediment and brown bullhead catfish tissues from the Black River in Lorain County, Ohio, declined by 65% and 93%, respectively, between 1980 and 1982. Sediment PAHs declined an additional 99% by 1987, coincident with the closure of a coking facility in 1983. Contemporaneously, liver cancer in 3- to 4-year-old brown bullheads declined to about one-quarter the 1982 frequency (10% versus 39%) by 1987, while the percentage of livers without any proliferative lesions doubled (42% versus 20%). These changes were significant within age group. Our data affirm a cause-and-effect relationship between PAH exposure and liver cancer in wild fish. The data also support the efficacy of natural, unassisted remediation once the source of the pollution is eliminated.
摘要
1980年至1982年间，俄亥俄州洛雷恩县黑河沉积物和褐首鲶鱼组织中的多环芳烃（PAHs）分别下降了65%和93%。到1987年，沉积物中的PAHs又下降了99%，这与1983年一家炼焦厂的关闭同时发生。与此同时，3至4岁褐首鲶鱼的肝癌发病率到1987年降至1982年发病率的约四分之一（10%对39%），而没有任何增殖性病变的肝脏比例翻了一番（42%对20%）。这些变化在同一年龄组内具有显著性。我们的数据证实了野生鱼类接触PAHs与肝癌之间的因果关系。数据还支持一旦消除污染源，自然、无辅助修复的有效性。
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