Zaĭtseva T S, Morozova M S, Goncharova V N, Asribekova M K, Karpova S K, Astakhova T M, Murashko L E
Vestn Ross Akad Med Nauk. 1994(12):13-6.
The levels of progesterone and estrogen receptors, cAMP and prostaglandins E2 and F2 alpha were studied in the decidua of pregnant women, which was obtained during surgical, spontaneous or prostaglandin-induced abortion or by pregnancy termination with vacuum aspiration after RU-486 treatment (before the onset of abortion). Our data have allowed the authors to suggest that (i) for the maintenance of normal activity of decidua during pregnancy, the following points are considerably important: the constant ratio of progesterone and estrogen receptors in favor of progesterone receptors, low PG levels and high cAMP levels; (ii) both spontaneous and induced abortion are characterized by decreases in the levels of progesterone receptor (which in turn changes the ratio of progesterone and estrogen receptors in favor of the latter), by increased PG levels and decreasing cAMP concentrations.
对孕妇蜕膜中的孕酮和雌激素受体、环磷酸腺苷（cAMP）以及前列腺素E2和F2α水平进行了研究。这些蜕膜取自手术流产、自然流产或前列腺素诱导流产的孕妇，或取自米非司酮治疗后（流产开始前）通过负压吸引终止妊娠的孕妇。我们的数据使作者能够提出：（i）对于维持孕期蜕膜的正常活性，以下几点相当重要：孕酮和雌激素受体的恒定比例，且有利于孕酮受体；低前列腺素水平和高环磷酸腺苷水平；（ii）自然流产和人工流产的特征均为孕酮受体水平降低（这反过来又改变了孕酮和雌激素受体的比例，有利于后者）、前列腺素水平升高以及环磷酸腺苷浓度降低。
