Ramsden J J, Li S Y, Heinzle E, Prenosil J E
Department of Biophysical Chemistry, Biocenter, The University, Basel, Switzerland.
Cytometry. 1995 Feb 1;19(2):97-102. doi: 10.1002/cyto.990190202.
A novel, on-line method of accurately parametrizing the shape of spreading cells is described. The substrate on which the cells are deposited serves as an optical waveguide. The method is based on the interaction between the evanescent part of the guided waves and the cells. No special labelling of the cells is required. A mathematical framework for interpreting the results is derived, and some illustrative results are presented.
本文描述了一种精确参数化扩展细胞形状的新型在线方法。细胞所附着的基质用作光波导。该方法基于导波的倏逝部分与细胞之间的相互作用。无需对细胞进行特殊标记。推导了用于解释结果的数学框架，并给出了一些说明性结果。
