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经典型和类固醇诱导型卡波西肉瘤的流式细胞术DNA分析

Flow cytometric DNA analysis of classic and steroid-induced Kaposi's sarcoma.

作者信息

Reizis Z, Trattner A, Katzenelson V, David M, Rotem A, Nativ O, Mor Y

机构信息

Department of Dermatology, Beilinson Medical Center, Petah Tiqva, Israel.

出版信息

Br J Dermatol. 1995 Apr;132(4):548-50. doi: 10.1111/j.1365-2133.1995.tb08709.x.

DOI:10.1111/j.1365-2133.1995.tb08709.x
PMID:7748744
Abstract

Flow cytometric DNA analysis of various tumours has indicated a correlation between the degree of malignancy and ploidy; results which could have clinical significance. We analysed the ploidy of Kaposi's sarcoma (KS) tumours, and classified the results according to clinical history and histological findings. We found that patients on steroid treatment had an aneuploid pattern, and most of the patients with classic-type KS had a diploid pattern on flow cytometry.

摘要

对各种肿瘤进行的流式细胞术DNA分析表明,恶性程度与倍性之间存在相关性;这些结果可能具有临床意义。我们分析了卡波西肉瘤(KS)肿瘤的倍性,并根据临床病史和组织学结果对结果进行了分类。我们发现,接受类固醇治疗的患者呈现非整倍体模式,而大多数经典型KS患者在流式细胞术检测中呈现二倍体模式。

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