Liu C, Zhao F, Li W, Zhu L
Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
Zhen Ci Yan Jiu. 1994;19(2):52-5.
In this study, extracellular recordings were made from wide dynamic range (WDR) neurons in lumbar segments of the spinal cord in rats transsected at the first lumbar segment. The nociceptive discharges of WDR neurons were depressed by weak electro-acupuncture applied to "Yanglingquan"-"Xuanzhong" points. The depression was blocked by i.v. administration of adenosine receptor antagonists, theophylline and caffeine. The observations indicate that depression of the nociceptive response of the WDR neurons induced by weak EA may be mediated by adenosine within the spinal cord.
在本研究中，对第一腰段横断的大鼠脊髓腰段的广动力范围（WDR）神经元进行了细胞外记录。对“阳陵泉”-“悬钟”穴施加弱电针可抑制WDR神经元的伤害性放电。静脉注射腺苷受体拮抗剂茶碱和咖啡因可阻断这种抑制作用。这些观察结果表明，弱电针诱导的WDR神经元伤害性反应的抑制可能由脊髓内的腺苷介导。
