萘普生治疗膝关节骨关节炎的双盲研究。
Double-blind study of Naproxen in osteoarthritis of the knee joint.
作者信息
Tanaka S, Ito T, Mori E, Muroga T, Nakajima A
出版信息
J Rheumatol. 1976 Mar;3(1):27-36.
PMID:775086
Abstract
To determine the effectiveness of naproxen in the treatment of osteoarthritis of the knee joint, a double-blind cross-over study against placebo was carried out on 61 patients. Statistically significant positive therapeutic effects were observed, including analgesia, increased mobility, decrease in joint swelling and improvement in activities of daily living. Side effects were infrequent, mild and disappeared rapidly.
摘要
为确定萘普生治疗膝关节骨关节炎的有效性，对61例患者进行了一项针对安慰剂的双盲交叉研究。观察到具有统计学意义的积极治疗效果，包括镇痛、活动能力增强、关节肿胀减轻以及日常生活活动改善。副作用不常见，症状轻微且迅速消失。
Zotero 插件