Krisher K K, Holdridge N B, Mustafa M M, Rinaldi M G, McGough D A
Children's Medical Center of Dallas, TX 75235, USA.
J Clin Microbiol. 1995 Mar;33(3):735-7. doi: 10.1128/jcm.33.3.735-737.1995.
Microascus cirrosus Curzi and its associated anamorphic state, Scopulariopsis, were recovered from the cutaneous lesion of a 12-year-old male who had undergone an autologous bone marrow transplantation for acute myelogenous leukemia. Histopathology sections from the biopsied lesion demonstrated septate hyphae consistent with a fungal etiology. Radiographic studies of the lungs subsequent to progression of the lesion revealed a consolidation in the right upper lobe suggesting a primary focus of infection. While M. cirrosus is fairly abundant in nature and widely distributed in stored grains in North America, this is, to our knowledge, the first reported human infection by this species. Salient characteristics for the identification of this dematiaceous ascomycete, M. cirrosus, will be presented.
从一名12岁男性的皮肤病变中分离出了卷枝微囊菌（Microascus cirrosus Curzi）及其相关的无性型拟青霉属（Scopulariopsis），该男性因急性髓性白血病接受了自体骨髓移植。活检病变的组织病理学切片显示有分隔的菌丝，符合真菌病因。病变进展后对肺部的影像学研究显示右上叶实变，提示有原发性感染灶。虽然卷枝微囊菌在自然界中相当常见，在北美储存的谷物中广泛分布，但据我们所知，这是该物种首次报道的人类感染病例。本文将介绍鉴定这种暗色子囊菌——卷枝微囊菌的显著特征。
