Gandhi G, Chowdhury J B, Sareen P K, Dhillon V P
Department of Human Genetics, Guru Nanak Dev University, Amritsar, India.
Mutat Res. 1995 Apr;346(4):203-6. doi: 10.1016/0165-7992(95)90036-5.
The genotoxicity of deltamethrin was studied in Swiss albino male mice (five animals/group) using the bone marrow micronucleus assay. Deltamethrin (two i.p. injections, 30 h and 6 h before sample collection) was found to induce micronuclei at 162.5 and 300.0 mg/kg body weight. A lower dose (32.5 mg/kg body weight) failed to induce a significant increase in micronuclei over the control level.
使用骨髓微核试验在瑞士白化雄性小鼠(每组五只动物)中研究了溴氰菊酯的遗传毒性。发现溴氰菊酯(在采集样本前30小时和6小时进行两次腹腔注射)在162.5和300.0毫克/千克体重时可诱导微核形成。较低剂量(32.5毫克/千克体重)未能使微核数量相比对照水平有显著增加。