来自白花葱和奥氏葱的甾体糖苷。

Steroidal glycosides from Allium albopilosum and A. ostrowskianum.

作者信息

Mimaki Y, Kawashima K, Kanmoto T, Sashida Y

机构信息

Tokyo College of Pharmacy, Japan.

出版信息

Phytochemistry. 1993 Oct;34(3):799-805. doi: 10.1016/0031-9422(93)85362-u.

DOI:10.1016/0031-9422(93)85362-u

PMID:7764153

Abstract

Chemical studies of the bulbs of Allium albopilosum and A. ostrowskianum have led to the isolation of two new steroidal saponins and four new cholestane glycosides together with several known compounds. The structures of the new compounds were established by the spectroscopic data, hydrolysis and chemical correlations as (25 R and S)-5 alpha-spirostane-2 alpha,3 beta,6 beta-triol 3-O-(O-beta-D-glucopyranosyl-(1-->2)-O-[3-O-acetyl-beta-D-xylopyranosyl- (1-->3)]-O-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside), (25R)-2-O-[(S)-3-hydroxy-3-methylglutaroyl]-5 alpha-spirostane-2 alpha, 3 beta, 6 beta-triol 3-O-(O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-xylopyranosyl-(1-->3)]-O- beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside), (22S)-cholest-5-ene-1 beta,3 beta,16 beta,22-tetraol 1-O-alpha-L-rhamnopyranoside 16-O-(O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside), 1 beta,3 beta,16 beta-trihydroxycholest-5-en-22-one 1-O-alpha-L-rhamnopyranoside 16-O-(O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside), 1 beta,3 beta,16 beta-trihydroxy-5 alpha-cholestan-22-one 1-O-alpha-L-rhamnopyranoside 16-O-(O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside) and (22S)-cholest-5-ene-1 beta,3 beta,16 beta,22-tetraol 16-O-(O-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranoside).

摘要

对绵枣儿和糙葶韭鳞茎的化学研究已导致分离出两种新的甾体皂苷和四种新的胆甾烷糖苷以及几种已知化合物。通过光谱数据、水解和化学关联确定了新化合物的结构，分别为(25R和S)-5α-螺旋甾烷-2α,3β,6β-三醇3-O-(O-β-D-吡喃葡萄糖基-(1→2)-O-[3-O-乙酰基-β-D-吡喃木糖基-(1→3)]-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷)、(25R)-2-O-[(S)-3-羟基-3-甲基戊二酰基]-5α-螺旋甾烷-2α,3β,6β-三醇3-O-(O-β-D-吡喃葡萄糖基-(1→2)-O-[β-D-吡喃木糖基-(1→3)]-O-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃半乳糖苷)、(22S)-胆甾-5-烯-1β,3β,16β,22-四醇1-O-α-L-鼠李吡喃糖苷16-O-(O-α-L-鼠李吡喃糖基-(1→3)-β-D-吡喃葡萄糖苷)、1β,3β,16β-三羟基胆甾-5-烯-22-酮1-O-α-L-鼠李吡喃糖苷16-O-(O-α-L-鼠李吡喃糖基-(1→3)-β-D-吡喃葡萄糖苷)、1β,3β,16β-三羟基-5α-胆甾烷-22-酮1-O-α-L-鼠李吡喃糖苷16-O-(O-α-L-鼠李吡喃糖基-(1→3)-β-D-吡喃葡萄糖苷)和(22S)-胆甾-5-烯-1β,3β,16β,22-四醇16-O-(O-β-D-吡喃葡萄糖基-(1→3)-β-D-吡喃葡萄糖苷)。