合成洋地黄毒苷配基糖苷的构效关系。
Structure-activity relationships of synthetic digitoxigenyl glycosides.
作者信息
Takechi M, Tanaka Y
机构信息
Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka, Japan.
出版信息
Phytochemistry. 1994 Nov;37(5):1421-3. doi: 10.1016/s0031-9422(00)90424-2.
PMID:7765759
Abstract
Antiviral, cytotoxic and anti-ATPase activities of 14 synthetic digitoxigenyl glycosides were compared with each other. The activities of those containing gentiobioside and melibioside were much weaker than the others. On the other hand, the three activities were highly correlated with each other.
摘要
比较了14种合成洋地黄毒糖基糖苷的抗病毒、细胞毒性和抗ATP酶活性。含有龙胆二糖苷和蜜二糖苷的那些糖苷的活性比其他糖苷弱得多。另一方面，这三种活性彼此高度相关。
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