Salikhova R A, Poroshenko G G
Vestn Ross Akad Med Nauk. 1995(1):58-61.
The antimutagenic activity of Angelica archangelica L. aqueous and alcohol extracts of thio-TEPA against mutagenicity was examined by the micronucleus test in murine bone marrow cells. The reduction of Thio-TEPA's mutagenic activity was more profound when the extracts were injected 2 hours before thio-TEPA treatment, as seen during simultaneous treatment. The observed reduction of micronuclear frequencies was as high as 77%.
通过小鼠骨髓细胞微核试验，检测了当归水提取物和硫代磷酸三乙酯醇提取物对硫代磷酸三乙酯诱变性的抗诱变活性。与同时处理时相比，在硫代磷酸三乙酯处理前2小时注射提取物时，硫代磷酸三乙酯诱变活性的降低更为显著。观察到的微核频率降低高达77%。
