DNA拓扑异构酶的作用机制。
The mechanisms of DNA topoisomerases.
作者信息
Roca J
机构信息
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
出版信息
Trends Biochem Sci. 1995 Apr;20(4):156-60. doi: 10.1016/s0968-0004(00)88993-8.
PMID:7770916
Abstract
Recent structural and mechanistic studies, as well as the discovery of new enzymes in the DNA topoisomerase family, allow these enzymes to be classified into three groups. Each group reflects the evolution of three different mechanistic strategies to manipulate DNA topology.
摘要
最近的结构和机制研究，以及DNA拓扑异构酶家族中新酶的发现，使得这些酶可以被分为三组。每组都反映了操纵DNA拓扑结构的三种不同机制策略的演变。
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