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马来西亚北部的脊髓灰质炎和麻疹血清学调查。

Poliomyelitis and measles serosurvey in northern Malaysia.

作者信息

Saraswathy T S, Sinniah M, Lee W S, Lye M S, Choo K E, Jusoh H

机构信息

Department of Tropical Medicine, Institute for Medical Research, Kuala Lumpur.

出版信息

Southeast Asian J Trop Med Public Health. 1994 Sep;25(3):565-8.

PMID:7777927
Abstract

In 1990 the Institute for Medical Research carried out a serosurvey in the state of Kelantan to study the age stratified immune prevalence rates for measles and poliomyelitis. Our findings indicate that 981 out of 1,097 (89%) of the population screened had measles antibodies and more than 90% (366 out of 400) had antibodies to all three serotypes of poliovirus. The susceptible group for measles was infants below one year of age, of whom 53.3% (8/15) did not have measles antibody. Of 400 subjects, 125 (31.3%) who were either incompletely vaccinated or had not been vaccinated against poliomyelitis, had polio neutralizing antibodies to all three poliovirus serotypes, suggesting herd immunity in the population. No high risk age group could be identified for poliomyelitis.

摘要

1990年,医学研究所(Institute for Medical Research)在吉兰丹州开展了一项血清学调查,以研究不同年龄组中麻疹和脊髓灰质炎的免疫流行率。我们的研究结果表明,在接受筛查的1097人中,有981人(89%)拥有麻疹抗体,超过90%(400人中的366人)拥有针对所有三种脊髓灰质炎病毒血清型的抗体。麻疹的易感人群是一岁以下的婴儿,其中53.3%(8/15)没有麻疹抗体。在400名受试者中,125人(31.3%)要么接种不完全,要么未接种脊髓灰质炎疫苗,但却拥有针对所有三种脊髓灰质炎病毒血清型的中和抗体,这表明该人群中存在群体免疫。未发现脊髓灰质炎的高危年龄组。

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