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挪威中年癌症女性的丧偶和离婚与总体生存率的关系

Widowhood and divorce in relation to overall survival among middle-aged Norwegian women with cancer.

作者信息

Kvikstad A, Vatten L J, Tretli S

机构信息

Department of Oncology, University Hospital, Trondheim, Norway.

出版信息

Br J Cancer. 1995 Jun;71(6):1343-7. doi: 10.1038/bjc.1995.261.

Abstract

The aim of the study was to examine the relations between widowhood and divorce and overall survival among women with cancer. All Norwegian women born between 1935 and 1954, and diagnosed with cancer between 1966 and 1990, were followed up until 1991. In all, 14,231 cases were followed up for a median length of approximately 4.5 years (mean = 6 years), and 4311 women died during follow-up. In addition to overall cancer, separate analyses have been made for cancer at specific sites. Widows had a risk of dying which was nearly identical to that of married women for all sites except colorectal cancer, for which widows had a 2-fold increased death rate compared with married women. Divorced women had an overall increased hazard ratio of 1.17 (95% CI 1.07-1.27), which was confined to cancer of the breast, lung and cervix. With few clear exceptions women with children had a better survival than nulliparous women (overall hazard ratio = 0.80, 95% CI 0.74-0.87).

摘要

该研究的目的是调查寡居和离婚与癌症女性的总生存率之间的关系。对所有1935年至1954年出生、1966年至1990年期间被诊断患有癌症的挪威女性进行随访,直至1991年。总共对14231例病例进行了随访,中位随访时间约为4.5年(平均 = 6年),4311名女性在随访期间死亡。除了总体癌症外,还对特定部位的癌症进行了单独分析。除结直肠癌外,寡居女性在所有部位的死亡风险与已婚女性几乎相同,结直肠癌方面,寡居女性的死亡率比已婚女性高出2倍。离婚女性的总体风险比为1.17(95%置信区间1.07 - 1.27),这仅限于乳腺癌、肺癌和宫颈癌。除少数明显例外情况外,有子女的女性比未生育女性的生存率更高(总体风险比 = 0.80,95%置信区间0.74 - 0.87)。

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