Tezel T, Günalp I, Tezel G
Clinic of Ophthalmology, Numune Hospital, Ankara, Turkey.
Doc Ophthalmol. 1994;88(2):113-25. doi: 10.1007/BF01204609.
Twenty-one macroaneurysms and related vessels of 19 patients were evaluated morphometrically. Macroaneurysms were classified into two groups as hemorrhagic and exudative in terms of their major clinical sign. Average diameters of the macroaneurysms were arranged in a Gaussian distribution curve (mean and standard deviation: 281.60 +/- 57.28 micrometers). Regarding the distribution curve based on this data macroaneurysm can be defined as being greater than 109.76 micrometers. Macroaneurysms were most frequent on the superotemporal vessels (52.38%), followed by the inferotemporal (38.10%), inferonasal (4.76%) and superonasal vessels. Average diameter (r = +0.68, p = 0.0006) and area (r = +0.71, p = 0.0003) of the macroaneurysms were significantly correlated to the diameter of the relevant arterial segments. The distribution of the macroaneurysms in respect to arterial bifurcation (chi 2 = 18.762, p = 0.0003) and arteriovenous crossings (chi 2 = 8.286, p = 0.0405) were nonrandom with macroaneurysms clustering near this points. Hemorrhagic macroaneurysms were significantly closer to the optic disc (p < 0.01) and were located on relatively larger arterioles (p < 0.01). They were also more circular (p < 0.01) in shape and greater in area (p < 0.01) and diameter (p < 0.01) than the exudative ones. These findings suggest that the location of the macroaneurysm is closely related to its clinical appearance.
对19例患者的21个大动脉瘤及相关血管进行了形态测量评估。根据主要临床体征，大动脉瘤分为出血性和渗出性两组。大动脉瘤的平均直径呈高斯分布曲线（均值和标准差：281.60±57.28微米）。根据该数据的分布曲线，大动脉瘤可定义为直径大于109.76微米。大动脉瘤最常见于颞上血管（52.38%），其次是颞下血管（38.10%）、鼻下血管（4.76%）和鼻上血管。大动脉瘤的平均直径（r = +0.68，p = 0.0006）和面积（r = +0.71，p = 0.0003）与相关动脉段的直径显著相关。大动脉瘤在动脉分叉处（χ2 = 18.762，p = 0.0003）和动静脉交叉处（χ2 = 8.286，p = 0.0405）的分布是非随机的，大动脉瘤在这些点附近聚集。出血性大动脉瘤明显更靠近视盘（p < 0.01），且位于相对较大的小动脉上（p < 0.01）。它们的形状也更圆（p < 0.01），面积（p < 0.01）和直径（p < 0.01）比渗出性大动脉瘤更大。这些发现表明大动脉瘤的位置与其临床表现密切相关。
