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耐甲氧西林金黄色葡萄球菌对互叶白千层精油的敏感性。

Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia.

作者信息

Carson C F, Cookson B D, Farrelly H D, Riley T V

机构信息

Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands.

出版信息

J Antimicrob Chemother. 1995 Mar;35(3):421-4. doi: 10.1093/jac/35.3.421.

DOI:10.1093/jac/35.3.421
PMID:7782258
Abstract

All 66 isolates of Staphylococcus aureus tested were susceptible to the essential oil of Melaleuca alternifolia, or tea tree oil, in disc diffusion and modified broth microdilution methods. Of the isolates tested, 64 were methicillin-resistant S. aureus (MRSA) and 33 were mupirocin-resistant. The MIC and MBC for 60 Australian isolates were 0.25% and 0.50%, respectively. Comparable results were obtained by co-workers in Britain using similar methods. These in-vitro results suggest tea tree oil may be useful in the treatment of MRSA carriage.

摘要

采用纸片扩散法和改良肉汤微量稀释法对66株金黄色葡萄球菌进行检测,结果显示,所有菌株对互叶白千层精油(即茶树油)均敏感。在检测的菌株中,64株为耐甲氧西林金黄色葡萄球菌(MRSA),33株对莫匹罗星耐药。60株澳大利亚分离株的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)分别为0.25%和0.50%。英国的同事采用类似方法也得到了类似结果。这些体外实验结果表明,茶树油可能对治疗MRSA携带有效。

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