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从摩洛哥患大肠杆菌病的鸡中分离出的大肠杆菌菌株的抗生素耐药性

Antibioresistance of Escherichia coli strains isolated in Morocco from chickens with colibacillosis.

作者信息

Amara A, Ziani Z, Bouzoubaa K

机构信息

Institut Agronomique et Vétérinaire Hassan II, Département de Pathologie Aviaire, Rabat-Instituts, Morocco.

出版信息

Vet Microbiol. 1995 Mar;43(4):325-30. doi: 10.1016/0378-1135(94)00101-2.

Abstract

Two hundred and fifty eight isolates of Escherichia coli were made from autopsied chickens showing lesions of avian colibacillosis. Antibiograms showed high levels of resistance (greater than 40%) to sulphonamides (SSS), oxytetracycline (OT), trimethoprim + sulphamethoxazole (STX) and chloramphenicol (C). Medium frequencies of resistances (from 15 to 40%) were noted for streptomycin (S), spectinomycin (SPT), nalidixic acid (NA), oxolinic acid (OA), flumequine (UB) and enrofloxacine (ENR). For ampicillin (AM), gentamicin (GM), nitrofurans (FT), colistin (CS) and rifampin (RA) the frequencies of resistance were low (less than 15%). A linked resistance was observed for the 4 quinolones. A significant percentage of isolates (82.5%) were resistant to at least 2 antimicrobial agents. The most frequent antibiotypes were: C.OT.SSS.STX (4.65%), C.OT.SSS.STX.OA.NA.UB.ENR (4.65%), AM.S.C.OT.SSS.STX (4.26%) and OT.SSS.STX (3.87%).

摘要

从患有禽大肠杆菌病病变的尸检鸡中分离出258株大肠杆菌。药敏谱显示,对磺胺类药物(SSS)、土霉素(OT)、甲氧苄啶+磺胺甲恶唑(STX)和氯霉素(C)具有高水平耐药性(大于40%)。对于链霉素(S)、大观霉素(SPT)、萘啶酸(NA)、恶喹酸(OA)、氟甲喹(UB)和恩诺沙星(ENR),耐药频率为中等(15%至40%)。对于氨苄西林(AM)、庆大霉素(GM)、呋喃类药物(FT)、黏菌素(CS)和利福平(RA),耐药频率较低(小于15%)。观察到4种喹诺酮类药物存在联合耐药性。相当比例的分离株(82.5%)对至少2种抗菌药物耐药。最常见的抗菌型为:C.OT.SSS.STX(4.65%)、C.OT.SSS.STX.OA.NA.UB.ENR(4.65%)、AM.S.C.OT.SSS.STX(4.26%)和OT.SSS.STX(3.87%)。

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