Blanco J E, Blanco M, Mora A, Blanco J
Department of Microbiology and Parasitology, Veterinary Faculty, University of Santiago de Compostela, Lugo, Spain.
J Clin Microbiol. 1997 Aug;35(8):2184-5. doi: 10.1128/jcm.35.8.2184-2185.1997.
Antimicrobial therapy is an important tool in reducing the enormous losses in the poultry industry caused by Escherichia coli infections (colibacillosis). However, resistance to existing antimicrobials is widespread and of concern to poultry veterinarians. Antimicrobial resistance testing of 468 avian E. coli strains isolated in Spain showed very high levels of resistance to trimethoprim-sulfamethoxazole (67%) and the new fluoroquinolones (13 to 24%). As these antimicrobial agents may cause cross-resistance with human enteric pathogens, prudent use of them in veterinary medicine is highly recommended.
抗菌疗法是减少家禽业因大肠杆菌感染(大肠杆菌病)造成巨大损失的一项重要手段。然而,对现有抗菌药物的耐药性广泛存在,这是家禽兽医所关注的问题。对西班牙分离出的468株禽源大肠杆菌菌株进行的抗菌药物耐药性检测显示,这些菌株对甲氧苄啶-磺胺甲恶唑(67%)和新型氟喹诺酮类药物(13%至24%)的耐药水平非常高。由于这些抗菌药物可能会与人类肠道病原体产生交叉耐药性,因此强烈建议在兽医学中谨慎使用它们。