Bell D W, Taguchi T, Jenkins N A, Gilbert D J, Copeland N G, Gilks C B, Zweidler-McKay P, Grimes H L, Tsichlis P N, Testa J R
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Cytogenet Cell Genet. 1995;70(3-4):263-7. doi: 10.1159/000134048.
The Gfi1 gene encodes a zinc finger protein which binds DNA and is involved in transcriptional regulation. Gfi1 was assigned to the central portion of mouse Chr 5 by interspecific backcross mapping and to human chromosome band 1p22 and rat chromosome band 14p22 by fluorescence in situ hybridization (FISH). Comparative mapping data presented here describes a new syntenic region between man and rodents.
Gfi1基因编码一种与DNA结合并参与转录调控的锌指蛋白。通过种间回交定位，Gfi1被定位于小鼠第5号染色体的中部；通过荧光原位杂交（FISH），它被定位于人类染色体带1p22和大鼠染色体带14p22。本文给出的比较定位数据描述了人与啮齿动物之间一个新的同线区域。
