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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Jaramillo-Juárez F, Ortiz G G, Rodriguez-Vázquez M L, Falcón-Franco M A, Feria-Velasco A

Departamento de Fisiología y Farmacologia, Universidad Autónoma de Aguascalientes, Ags, Mexico.

Gen Pharmacol. 1995 May;26(3):649-53. doi: 10.1016/0306-3623(95)94004-z.

Acute effects of Karwinskia humboldtiana (Kh) were studied in some renal functions and structural patterns of renal tissue. 2. Haemodynamic changes were observed with decrements of the glomerular filtration rate, renal plasma flow and filtration fraction during acute intoxication. 3. A marked increment in the fractional excretion of sodium was observed in the rats treated with tullidora fruits (Kh). 4. Cloudy swelling and hydropic degeneration was seen 72 hr after intoxication, mainly in the proximal convoluted tubules.

研究了洪堡卡氏木（Kh）对部分肾功能及肾组织结构模式的急性影响。2. 在急性中毒期间，观察到血流动力学变化，肾小球滤过率、肾血浆流量和滤过分数均下降。3. 在用图利多拉果实（Kh）处理的大鼠中，观察到钠分数排泄显著增加。4. 中毒72小时后可见混浊肿胀和水样变性，主要发生在近端曲管。

Jaramillo-Juárez F, Ortiz G G, Rodriguez-Vázquez M L, Falcón-Franco M A, Feria-Velasco A

Departamento de Fisiología y Farmacologia, Universidad Autónoma de Aguascalientes, Ags, Mexico.

Gen Pharmacol. 1995 May;26(3):649-53. doi: 10.1016/0306-3623(95)94004-z.

Acute effects of Karwinskia humboldtiana (Kh) were studied in some renal functions and structural patterns of renal tissue. 2. Haemodynamic changes were observed with decrements of the glomerular filtration rate, renal plasma flow and filtration fraction during acute intoxication. 3. A marked increment in the fractional excretion of sodium was observed in the rats treated with tullidora fruits (Kh). 4. Cloudy swelling and hydropic degeneration was seen 72 hr after intoxication, mainly in the proximal convoluted tubules.

研究了洪堡卡氏木（Kh）对部分肾功能及肾组织结构模式的急性影响。2. 在急性中毒期间，观察到血流动力学变化，肾小球滤过率、肾血浆流量和滤过分数均下降。3. 在用图利多拉果实（Kh）处理的大鼠中，观察到钠分数排泄显著增加。4. 中毒72小时后可见混浊肿胀和水样变性，主要发生在近端曲管。