Gregory T M, Heckmann R A, Francis R S
Department of Physical Education--Sports, Brigham Young University, USA.
J Manipulative Physiol Ther. 1995 Feb;18(2):72-8.
To determine the comparative rate of resolution of a contusion resulting from mechanical trauma to skeletal muscle, as a function of one of four exercise regimens.
Randomized control trial. The four exercise regimens were: running with its onset immediately after injury, running with a 72 hr delay after injury, swimming with immediate onset, or swimming with a 72 hr delay. Control did not exercise.
Small-animal laboratory.
Male Sprague-Dawley rats.
A small animal traumatizing machine applied to the biceps femoris.
The rate of contusion resolution was determined by a manual count of erythrocytes, leukocytes and collagen fibers in the contusion, and the data were analyzed using analysis of variance.
Exercise of any type produced a greater decline in erythrocyte count (28.2% after 32 days vs. control) than no exercise. Immediate onset of any of the exercise regimens after injury resulted in a greater decline in erythrocyte count (32.7% after 32 days vs. control) and in leukocyte count (17.3% after 32 days vs. control) than delayed onset. Running with either immediate or delayed onset of exercise after injury produced a greater decline in erythrocyte count (36.2% after 32 days vs. control) than swimming. Running with its onset immediately after injury produced the greatest overall rate of decrease in erythrocyte count (44.8% after 32 days vs. control), and the second greatest overall rate of decrease in leukocyte count (15.0% after 32 days vs. control).
Running with immediate onset is the regimen of choice. Any of the given exercises is preferable to no exercise, immediate onset of exercise is preferable to delayed onset, and running is preferable to swimming.
确定骨骼肌机械性创伤所致挫伤的愈合速率，并将其作为四种运动方案之一的函数进行比较。
随机对照试验。四种运动方案分别为：受伤后立即开始跑步、受伤72小时后开始跑步、受伤后立即开始游泳、受伤72小时后开始游泳。对照组不进行运动。
小动物实验室。
雄性斯普拉格-道利大鼠。
使用小动物创伤机器作用于股二头肌。
通过手动计数挫伤部位的红细胞、白细胞和胶原纤维来确定挫伤的愈合速率，并使用方差分析对数据进行分析。
与不运动相比，任何类型的运动都会使红细胞计数下降幅度更大（32天后下降28.2%，与对照组相比）。受伤后立即开始任何一种运动方案，红细胞计数下降幅度（32天后下降32.7%，与对照组相比）和白细胞计数下降幅度（32天后下降17.3%，与对照组相比）均大于延迟开始运动。受伤后立即或延迟开始跑步，红细胞计数下降幅度（32天后下降36.2%，与对照组相比）大于游泳。受伤后立即开始跑步，红细胞计数总体下降速率最大（32天后下降44.8%，与对照组相比），白细胞计数总体下降速率次之（32天后下降15.0%，与对照组相比）。
受伤后立即开始跑步是首选方案。任何一种给定的运动都优于不运动，运动立即开始优于延迟开始，跑步优于游泳。
