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诊断阿尔茨海默病对就诊频率的影响:一项病例对照研究。

The effect of diagnosing Alzheimer's disease on frequency of physician visits: a case-control study.

作者信息

McCormick W C, Kukull W A, van Belle G, Bowen J D, Teri L, Larson E B

机构信息

Division of Geriatrics, University of Washington, Seattle 98195, USA.

出版信息

J Gen Intern Med. 1995 Apr;10(4):187-93. doi: 10.1007/BF02600253.

Abstract

OBJECTIVE

Two groups of elderly subjects were studied to see whether patterns of visits to physicians changed after one group received the diagnosis of Alzheimer's disease.

DESIGN

Case-control study.

SETTING

Health maintenance organization (HMO).

PATIENTS/PARTICIPANTS: Two groups of ambulatory subjects (mean age 77 years) were enrolled from an HMO population for this case-control study: 120 cases had probable Alzheimer's disease diagnosed at enrollment, and another 120 cognitively intact controls with similar comorbidity were enrolled after being frequency-matched for age and gender. Exclusion criteria were nursing home admission and death during the study period.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Medical records were examined for a four-year period: two years prior to and two years following enrollment and diagnosis. Physician visits declined slightly after enrollment for the persons receiving the diagnosis of Alzheimer's disease [17.5/2 years prior vs 16.5/2 years after (NS)], whereas visits increased over time for the controls [13.7/2 vs 16.3/2 (p < 0.05)], hence the rates were similar after enrollment [16.5 vs 16.3 (NS)]. The proportion of subjects with fewer visits during the period after enrollment was higher among the cases than it was among the controls [54% vs 37%; odds ratio = 2.0 (95% confidence interval = 1.6, 3.1)]. Hospitalizations and emergency department use did not change significantly after enrollment.

CONCLUSIONS

Physician visit frequency was high before, then decreased after, demented patients received their diagnosis, approaching the frequency in a control population without dementia. This phenomenon cannot be accounted for by nursing home placement, comorbidity, or mortality. Increased hospitalization and emergency department use did not ensue after diagnosis.

摘要

目的

对两组老年受试者进行研究,以观察其中一组被诊断为阿尔茨海默病后,其看医生的模式是否发生变化。

设计

病例对照研究。

地点

健康维护组织(HMO)。

患者/参与者:从HMO人群中招募了两组门诊受试者(平均年龄77岁)进行这项病例对照研究:120例在入组时被诊断为可能患有阿尔茨海默病,另外120例认知功能正常的对照者在按年龄和性别进行频率匹配后入组,他们具有相似的合并症。排除标准为在研究期间入住疗养院和死亡。

干预措施

无。

测量指标及主要结果

对医疗记录进行了为期四年的检查:入组和诊断前两年以及入组和诊断后两年。被诊断为阿尔茨海默病的患者在入组后看医生的次数略有下降[诊断前两年为17.5次/两年,诊断后两年为16.5次/两年(无统计学差异)],而对照组的看医生次数随时间增加[13.7次/两年对16.3次/两年(p<0.05)],因此入组后两组的看医生率相似[16.5次对16.3次(无统计学差异)]。入组后看医生次数减少的受试者比例在病例组中高于对照组[54%对37%;优势比=2.0(95%置信区间=1.6,3.1)]。入组后住院和急诊就诊情况没有显著变化。

结论

痴呆患者在诊断前看医生的频率较高,诊断后降低,接近无痴呆对照组的频率。这种现象不能用入住疗养院、合并症或死亡率来解释。诊断后住院和急诊就诊情况并未增加。

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