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加拿大社区样本中的神经性贪食症:患病率及亚组比较

Bulimia nervosa in a Canadian community sample: prevalence and comparison of subgroups.

作者信息

Garfinkel P E, Lin E, Goering P, Spegg C, Goldbloom D S, Kennedy S, Kaplan A S, Woodside D B

机构信息

Clarke Institute of Psychiatry, Toronto, Ont., Canada.

出版信息

Am J Psychiatry. 1995 Jul;152(7):1052-8. doi: 10.1176/ajp.152.7.1052.

DOI:10.1176/ajp.152.7.1052
PMID:7793442
Abstract

OBJECTIVE

Previous epidemiological studies of bulimia nervosa have generated differing estimates of the incidence and prevalence of the disorder. These differences are attributable, in part, to varying definitions of the illness and a range of methodologies. The authors sought to define the prevalence of bulimia nervosa in a nonclinical community sample, examine the clinical significance of DSM-III-R threshold criteria, and examine comorbidity.

METHOD

Subjects across Ontario (N = 8,116) were assessed with a structured interview, the World Health Organization Composite International Diagnostic Interview, with specific questions added for bulimia nervosa. Subjects who met DSM-III-R criteria for bulimia nervosa were compared with those who were missing only the frequency criterion (two or more binge-eating episodes per week for 3 months).

RESULTS

In this sample, the lifetime prevalence of bulimia nervosa was 1.1% for female subjects and 0.1% for male subjects. The subjects with full- and partial-syndrome bulimia nervosa showed significant vulnerability for mood and anxiety disorders. Lifetime rates of alcohol dependence were high in the full-syndrome group. Rates of parental psychopathologies were high in both bulimic groups but tended to be higher in the subjects with full-syndrome bulimia nervosa. Both bulimic groups were significantly more likely to experience childhood sexual abuse than a normal female comparison group.

CONCLUSIONS

This study confirms other prevalence estimates of bulimia nervosa and its comorbid diagnoses from studies that were based on sound methodologies. It also points to the arbitrary aspects of the frequency of binge eating as a diagnostic threshold criterion for the disorder.

摘要

目的

先前对神经性贪食症的流行病学研究对该疾病的发病率和患病率得出了不同的估计。这些差异部分归因于疾病定义的不同和一系列方法学的差异。作者试图确定非临床社区样本中神经性贪食症的患病率,检验《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)阈值标准的临床意义,并研究共病情况。

方法

对安大略省的8116名受试者进行了结构化访谈,即世界卫生组织综合国际诊断访谈,并增加了有关神经性贪食症的特定问题。将符合DSM-III-R神经性贪食症标准的受试者与仅缺失频率标准(每周有两次或更多次暴饮暴食发作,持续3个月)的受试者进行比较。

结果

在这个样本中,女性受试者神经性贪食症的终生患病率为1.1%,男性受试者为0.1%。患有完全型和部分型神经性贪食症的受试者在情绪和焦虑障碍方面表现出显著的易感性。完全型综合征组酒精依赖的终生患病率很高。两个贪食症组中父母患精神疾病的比例都很高,但在完全型神经性贪食症受试者中往往更高。与正常女性对照组相比,两个贪食症组经历童年性虐待的可能性都显著更高。

结论

这项研究证实了基于可靠方法学的其他关于神经性贪食症及其共病诊断的患病率估计。它还指出了暴饮暴食频率作为该疾病诊断阈值标准的随意性。

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