Strangert K, Carlström G, Jeansson S, Nord C E
Acta Paediatr Scand. 1976 Jul;65(4):455-63. doi: 10.1111/j.1651-2227.1976.tb04914.x.
Viral and bacterial infections in 20 children under 3 years of age were studied in a day centre for 12 weeks. Febrile illnesses were found on one occasion in each of 11 children but no serious infection occurred. Pneumococci types 6, 9, or 19 were isolated from all children but more often from those with rhinitis or cough. The individual child had an average of 2 viral infections. Adenovirus types 1, 2, 5, coxsackievirus type B5, herpes simplex virus or respiratory syncytial virus was isolated from 12% of the oropharynx swabs and 40% of the fecal specimens. When a virus was first isolated from the oropharynx, the children were asymptomatic or had only rhinitis in 73% of the cases which might indicate that the dismissing of symptomatic children is of limited value in controlling the spread of infections in a day care centre. Cytomegalovirus was recovered from 22% of the urine specimens. Carrier frequency of cytomegalovirus was 23% in 40 other children attending one of 13 different day care centers. Because asymptomatic cytomegalovirus infections apparently occur frequently among small children in Sweden, it seems reasonable not to take pronounced measures of isolating the children in the relatively few recognized cases of cytomegalovirus infections.
在一家日托中心对20名3岁以下儿童的病毒和细菌感染情况进行了为期12周的研究。11名儿童各有一次发热性疾病发作,但未发生严重感染。从所有儿童中均分离出6型、9型或19型肺炎球菌,但在患有鼻炎或咳嗽的儿童中分离率更高。每个儿童平均有2次病毒感染。从12%的口咽拭子和40%的粪便标本中分离出1型、2型、5型腺病毒、B5型柯萨奇病毒、单纯疱疹病毒或呼吸道合胞病毒。当首次从口咽分离出病毒时,73%的病例中儿童无症状或仅有鼻炎,这可能表明在日托中心将有症状的儿童送走对于控制感染传播的价值有限。从22%的尿液标本中检出巨细胞病毒。在13个不同日托中心之一的其他40名儿童中,巨细胞病毒携带率为23%。由于在瑞典幼儿中无症状巨细胞病毒感染显然很常见,因此对于相对较少的已确认巨细胞病毒感染病例,似乎没有必要采取明显的隔离儿童措施。