Bottini P B, Carr A A, Prisant L M, Flickinger F W, Allison J D, Gottdiener J S
Department of Medicine, Medical College of Georgia, Augusta, USA.
Am J Hypertens. 1995 Mar;8(3):221-8. doi: 10.1016/0895-7061(94)00178-E.
Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy, precision, and reliability of LVM estimates by MRI as compared to data obtained by ECHO in hypertensive patients. Accuracy referred to the comparison of LVM by MRI to anatomical LVM determined by autopsy. Precision was examined using 34 duplicate MRI images and by blindly reading 24 duplicate M-mode strips. Reliability was assessed by MRI in four subjects over 2 months, and by ECHO in 22 hypertensive patients over 2 weeks. Agreement between MRI and ECHO estimates of LVM was determined in the same 17 hypertensive patients using linear regression. MRI LVM estimates were within 17.5 g (95% CI) of the true LVM. The linear agreement between MRI and ECHO estimates of LVM could be described by the equation MRI = 0.61 x ECHO + 49.57 (r = 0.63, P < .01). The precision of LVM by MRI (11 g) was over twice that observed with ECHO (26 g). The reliability of MRI LVM estimates was more consistent (+/- 8 g) than that for ECHO (+/- 49 g). MRI appears to be a more precise and reliable method for measuring LVM, and would be more suitable than ECHO for the clinical evaluation of the individual patient.
超声心动图（ECHO）对于记录患者群体左心室质量（LVM）的变化很有用，但对于个体患者可能因变异性过大而无法使用。磁共振成像（MRI）可能是一种更精确、更可靠的量化左心室质量的方法。本研究报告了与ECHO在高血压患者中获得的数据相比，MRI估计LVM的准确性、精密度和可靠性。准确性是指将MRI测得的LVM与尸检确定的解剖学LVM进行比较。使用34张重复的MRI图像并通过盲读24条重复的M型条带来检查精密度。通过对4名受试者进行为期2个月的MRI检查以及对22名高血压患者进行为期2周的ECHO检查来评估可靠性。在相同的17名高血压患者中，使用线性回归确定MRI和ECHO对LVM估计值之间的一致性。MRI对LVM的估计值与真实LVM相差在17.5 g（95% CI）以内。MRI和ECHO对LVM估计值之间的线性一致性可用方程MRI = 0.61×ECHO + 49.57来描述（r = 0.63，P <.01）。MRI测量LVM的精密度（11 g）是ECHO观察值（26 g）的两倍多。MRI对LVM估计值的可靠性（±8 g）比ECHO（±49 g）更一致。MRI似乎是一种更精确、更可靠的测量LVM的方法，并且比ECHO更适合个体患者的临床评估。
