Schneider L G
WHO Collaborating Centre for Rabies Surveillance and Research, Tübingen, Germany.
Dev Biol Stand. 1995;84:49-54.
Many years of research and observations on bait uptake, efficacy, behavioural studies of foxes, reduction and elimination of rabies, population dynamics of foxes following oral vaccination, as well as annual exchanges of researchers' experiences, formed the scientific background for field trials extending over many years. These are the most extensive field studies for the testing of a rabies vaccine so far. The use of the techniques and strategies of oral immunisation of foxes against rabies using SAD B19 can eliminate wildlife rabies among foxes and raccoon dogs, as European experience has shown. The disease then also disappears completely in domestic animals and man.
多年来对诱饵摄取、效果、狐狸行为研究、狂犬病的减少与消除、口服疫苗接种后狐狸的种群动态进行的研究和观察,以及研究人员每年的经验交流,构成了多年来进行现场试验的科学背景。这些是迄今为止针对狂犬病疫苗测试开展的最广泛的现场研究。正如欧洲的经验所示,采用SAD B19对狐狸进行狂犬病口服免疫的技术和策略,可以消除狐狸和貉中的野生动物狂犬病。随后,这种疾病在家畜和人类中也会完全消失。