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狂犬病病毒疫苗

Rabies virus vaccines.

作者信息

Schneider L G

机构信息

WHO Collaborating Centre for Rabies Surveillance and Research, Tübingen, Germany.

出版信息

Dev Biol Stand. 1995;84:49-54.

PMID:7796967
Abstract

Many years of research and observations on bait uptake, efficacy, behavioural studies of foxes, reduction and elimination of rabies, population dynamics of foxes following oral vaccination, as well as annual exchanges of researchers' experiences, formed the scientific background for field trials extending over many years. These are the most extensive field studies for the testing of a rabies vaccine so far. The use of the techniques and strategies of oral immunisation of foxes against rabies using SAD B19 can eliminate wildlife rabies among foxes and raccoon dogs, as European experience has shown. The disease then also disappears completely in domestic animals and man.

摘要

多年来对诱饵摄取、效果、狐狸行为研究、狂犬病的减少与消除、口服疫苗接种后狐狸的种群动态进行的研究和观察,以及研究人员每年的经验交流,构成了多年来进行现场试验的科学背景。这些是迄今为止针对狂犬病疫苗测试开展的最广泛的现场研究。正如欧洲的经验所示,采用SAD B19对狐狸进行狂犬病口服免疫的技术和策略,可以消除狐狸和貉中的野生动物狂犬病。随后,这种疾病在家畜和人类中也会完全消失。

相似文献

1
Rabies virus vaccines.狂犬病病毒疫苗
Dev Biol Stand. 1995;84:49-54.
2
Oral vaccination of wildlife against rabies: opportunities and challenges in prevention and control.野生动物狂犬病口服疫苗接种:预防与控制中的机遇与挑战
Dev Biol (Basel). 2004;119:173-84.
3
Development of a recombinant vaccinia-rabies vaccine for oral vaccination of foxes against rabies.用于狐狸口服狂犬病疫苗接种的重组痘苗狂犬病疫苗的研制。
Dev Biol Stand. 1992;79:105-11.
4
[Safety and efficacy of an antirabies vaccine consisting of recombinant vaccinia-rabies virus administered orally to the fox, dog and cat].[口服重组痘苗狂犬病病毒抗狂犬病疫苗对狐狸、狗和猫的安全性和有效性]
Ann Rech Vet. 1989;20(2):195-204.
5
Deliberate release of a recombinant vaccinia-rabies virus for vaccination of wild animals against rabies.故意释放重组痘苗狂犬病病毒用于野生动物狂犬病疫苗接种。
Microb Releases. 1993 Mar;1(4):191-5.
6
The rabies elimination programme in Estonia using oral rabies vaccination of wildlife: preliminary results.爱沙尼亚通过对野生动物进行口服狂犬病疫苗接种开展的狂犬病消除计划:初步结果。
Dev Biol (Basel). 2008;131:239-47.
7
[Oral vaccination of foxes against rabies in free game areas--a field trial].[在自由狩猎区对狐狸进行狂犬病口服疫苗接种——一项现场试验]
Tierarztl Prax. 1986;14(3):397-403.
8
Safety and efficacy of the oral rabies vaccine SAG2 in raccoon dogs.口服狂犬病疫苗SAG2对貉的安全性和有效性。
Vaccine. 2006 May 15;24(20):4386-92. doi: 10.1016/j.vaccine.2006.02.057. Epub 2006 Mar 24.
9
[Experiences with oral immunization of foxes against rabies in Hesse].[黑森州狐狸口服狂犬病疫苗的经验]
Tierarztl Prax. 1986;14(2):185-96.
10
Efficacy of a square presentation of V-RG vaccine baits in red fox, domestic dog and raccoon dog.V-RG疫苗诱饵方形剂型对赤狐、家犬和貉的有效性。
Dev Biol (Basel). 2008;131:257-64.

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Recombinant rabies virus vaccine strain SAD-l16 inoculated intracerebrally in young mice produces a severe encephalitis with extensive neuronal apoptosis.重组狂犬病病毒疫苗株SAD-l16经脑内接种幼年小鼠后,会引发严重的脑炎,并伴有广泛的神经元凋亡。
Can J Vet Res. 2005 Apr;69(2):100-5.