Van Damme P, Cramm M, Van der Auwera J C, Vranckx R, Meheus A
Department of Epidemiology and Community Medicine, University of Antwerp, Belgium.
Lancet. 1995 Jan 7;345(8941):27-9. doi: 10.1016/s0140-6736(95)91155-3.
In 1991-92, a cross-sectional survey in Flanders (Belgium) for hepatitis B virus (HBV) markers among 277 relatives of institutionalised mentally handicapped persons to evaluate the prevalence of hepatitis B and the risk of infection showed that relatives of an HBV positive resident were 7.6 times more likely to be infected than relatives of an HBV seronegative mentally handicapped person. HBV infection among the family members could be attributed in 83% to exposure to an HBV positive resident. This study demonstrated the importance of horizontal transmission among relatives of institutionalised mentally handicapped people, even if family contact is reduced to weekend and holiday activities. We recommend that HBV vaccination policy should be expanded to include relatives of institutionalised mentally retarded people.
1991 - 1992年，在比利时弗拉芒地区针对277名收容机构中智力障碍者的亲属开展了一项关于乙肝病毒（HBV）标志物的横断面调查，以评估乙肝的患病率和感染风险。结果显示，HBV阳性患者的亲属被感染的可能性是HBV血清阴性智力障碍者亲属的7.6倍。家庭成员中的HBV感染有83%可归因于接触HBV阳性患者。该研究表明，即使家庭接触仅限于周末和节假日活动，在收容机构中智力障碍者的亲属之间水平传播也很重要。我们建议扩大HBV疫苗接种政策，将收容机构中智力发育迟缓者的亲属纳入其中。
