Di Paolo N, Guarnieri A, Garosi G, Sacchi G, Mangiarotti A M, Di Paolo M
Nephrology and Dialysis Unit, USL 30, Siena Regional Hospital, Italy.
Nephrol Dial Transplant. 1994;9 Suppl 4:116-20.
Mysterious deaths of archeologists after opening Egyptian tombs have been suspected, but never proved, to be secondary to inhalation of mycotoxin. We observed a case of acute renal failure (ARF) due to inhalation of ochratoxin A produced by a mould of the species Aspergillus ochraceus. After working 8 h in a granary closed for several months, a farmer and his wife suffered respiratory distress; the woman developed non-oliguric ARF and biopsy revealed tubulonecrosis. A strain of Aspergillus ochraceus producing ochratoxin was isolated from the wheat.
考古学家在打开埃及古墓后离奇死亡，人们怀疑（但从未证实）这是吸入霉菌毒素所致。我们观察到一例因吸入赭曲霉属真菌产生的赭曲霉毒素A而导致急性肾衰竭（ARF）的病例。一名农民和他的妻子在一个封闭了几个月的谷仓里工作8小时后，出现了呼吸窘迫；该女子发展为非少尿型急性肾衰竭，活检显示肾小管坏死。从小麦中分离出了一株产生赭曲霉毒素的赭曲霉。
