Tison F, Dartigues J F, Dubes L, Zuber M, Alperovitch A, Henry P
Department of Neurology, Hôpital Pellegrin, Villejuif, France.
Acta Neurol Scand. 1994 Aug;90(2):111-5. doi: 10.1111/j.1600-0404.1994.tb02689.x.
We investigated the prevalence of Parkinson's disease in a representative sample of the elderly population living in the Gironde département, France. Among 3149 people over age 65, the prevalence ratio for Parkinson's disease was 1.4%, without significant difference between men and women. We found that age-specific prevalence ratios increased with age from 0.5% in the age group 65 to 69 to 6.1% in individuals over age 90. This age pattern is consistent with that found in other population-based studies. Interestingly, the slope of age-specific prevalence ratios for Parkinson's disease was similar to that previously reported for Lewy bodies. Our study showed that a high proportion (42%) of Parkinson's disease cases in elderly subjects living in institutions were undiagnosed.
我们调查了居住在法国吉伦特省的老年人群代表性样本中帕金森病的患病率。在3149名65岁以上的人群中，帕金森病的患病率为1.4%，男性和女性之间无显著差异。我们发现，特定年龄患病率随着年龄增长而上升，从65至69岁年龄组的0.5%升至90岁以上人群的6.1%。这种年龄模式与其他基于人群的研究结果一致。有趣的是，帕金森病特定年龄患病率的斜率与先前报道的路易体病相似。我们的研究表明，居住在养老院的老年受试者中，有很大比例（42%）的帕金森病病例未被诊断出来。
