Shinozawa T, Shida H
J Bacteriol. 1976 Jun;126(3):1025-9. doi: 10.1128/jb.126.3.1025-1029.1976.
lad (lambda adsorption), an Escherichia coli mutant that loses the ability to adsorb lambda phage immediately after a shift to high temperature (e.g., 42 C), was isolated. This property for phage adsorption is irreversible and has been observed with phage lambda and 21 but not with phages 434, phi 170, and phi 80. A crude receptor preparation, extracted from lad cells will cholate-ethylenediaminetetraacetic acid by the procedure of Randall-Hazelbauer and Schwartz (1973), inactivated the phage lambda only at low temperature.
lad（λ吸附）是一种大肠杆菌突变体，在转移到高温（如42℃）后立即丧失吸附λ噬菌体的能力。这种噬菌体吸附特性是不可逆的，并且已在λ噬菌体和21噬菌体中观察到，但在434噬菌体、φ170噬菌体和φ80噬菌体中未观察到。按照Randall-Hazelbauer和Schwartz（1973年）的方法，用胆酸盐-乙二胺四乙酸从lad细胞中提取的粗受体制剂仅在低温下使λ噬菌体失活。
