Campbell J, Dunn T
Accident and Emergency Department, St John's Hospital at Howden, Livingston.
J Accid Emerg Med. 1994 Sep;11(3):178-82. doi: 10.1136/emj.11.3.178.
One hundred patients who presented to the accident and emergency (A&E) department with an acute ankle sprain were entered into a study to determine the efficacy of topical ibuprofen cream by using a double-blind placebo controlled design in a single type of soft-tissue injury. The subjects were given either topical ibuprofen cream or a placebo cream in addition to the standard management of the department. Patients kept diaries recording walking ability and pain visual analogue scales for resting, standing and walking. A total of 51 patients returned diaries that were suitable for analysis. Patients using the topical ibuprofen cream had significant reduction in pain scores over the first 48 h of treatment.
100名因急性踝关节扭伤前往急诊部就诊的患者参与了一项研究，该研究采用双盲安慰剂对照设计，针对单一类型的软组织损伤来确定外用布洛芬乳膏的疗效。除了该科室的标准治疗外，研究对象被给予外用布洛芬乳膏或安慰剂乳膏。患者记录日记，记录行走能力以及静息、站立和行走时的疼痛视觉模拟评分。共有51名患者交回了适合分析的日记。使用外用布洛芬乳膏的患者在治疗的前48小时内疼痛评分显著降低。
