Ferracuti S, Seri S, Mattia D, Cruccu G
Department of Psychiatry and Medical Psychology, Università degli Studi La Sapienza, Rome, Italy.
Int J Psychophysiol. 1994 Aug;17(3):261-8. doi: 10.1016/0167-8760(94)90068-x.
In a study designed to investigate the neurophysiological correlates of the Cold Water Pressor Test, a standardized experimental model of tonic pain, spectral EEGs were examined during the test in 15 young right-handed adults. Each subject performed a "cold water" and a "warm water" session. The subject immersed in cold water (0 degree C) either the right or the left hand alone, in a randomized way. EEG activity was recorded for an initial 3 min baseline and for the first and second minute epochs after immersion. A further EEG recording was obtained after a 30-min rest. Pain intensity was measured with a visual analogue scale. The EEG recordings showed several patterns of cortical activation during the test. Alpha 2 desynchronization was more evident on the contralateral parietal electrodes of the stimulated hand and lasted longer over all the right hemisphere. Delta activity increased bilaterally, predominantly in the frontal leads. Stimulation of the left hand resulted in a higher delta increase during the second minute after immersion.
在一项旨在研究冷水升压试验（一种紧张性疼痛的标准化实验模型）的神经生理相关性的研究中，对15名年轻右利手成年人在试验过程中的脑电图频谱进行了检查。每个受试者都进行了一次“冷水”和一次“温水”试验。受试者以随机方式单独将右手或左手浸入冷水中（0摄氏度）。在最初的3分钟基线以及浸入后的第一分钟和第二分钟时段记录脑电图活动。在休息30分钟后再次进行脑电图记录。使用视觉模拟量表测量疼痛强度。脑电图记录显示在试验过程中皮层激活有几种模式。α2去同步化在受刺激手的对侧顶叶电极上更明显，并且在整个右半球持续时间更长。δ活动双侧增加，主要在额叶导联。浸入后第二分钟，刺激左手导致δ增加更高。
