Sugai E, Srur G, Vazquez H, Benito F, Mauriño E, Boerr L A, Bai J C
Hospital de Gastroenterologia, Universidad del Salvador, Buenos Aires, Argentina.
J Clin Gastroenterol. 1994 Oct;19(3):206-9. doi: 10.1097/00004836-199410000-00007.
Steatocrit is a semiquantitative method for determination of fat content in fecal samples. Previous studies, mostly performed in children, reported controversial results. The aim of our study was to compare the determination of fat content in 148 fecal samples by two methods: the conventional van de Kamer and the steatocrit. Seventy-seven fecal samples had steatorrhea (> 7 g/day). The upper normal limit for the steatocrit (determined by the mean +/- 2 SD of samples without steatorrhea) was 2.1%. The steatocrit showed a sensitivity of 87%, specificity of 97%, and positive and negative predictive values of 97 and 87%, respectively. When fecal fat excretion > 20 g/day was evaluated, sensitivity increased to 98%. A significant linear correlation was found between steatocrit and the quantitative chemical method (r = 0.80; p < 0.0001). In conclusion, the steatocrit is satisfactory in the discrimination of patients with and without fat malabsorption. It is a simple, rapid, inexpensive, and reliable semiquantitative test that can be used when other methods are impractical.
脂肪细胞比容是一种用于测定粪便样本中脂肪含量的半定量方法。以往的研究大多在儿童中进行,结果存在争议。我们研究的目的是通过两种方法比较148份粪便样本中的脂肪含量:传统的范德卡默法和脂肪细胞比容法。77份粪便样本有脂肪泻(>7克/天)。脂肪细胞比容的正常上限(由无脂肪泻样本的均值±2个标准差确定)为2.1%。脂肪细胞比容的敏感性为87%,特异性为97%,阳性和阴性预测值分别为97%和87%。当评估粪便脂肪排泄>20克/天时,敏感性增加到98%。脂肪细胞比容与定量化学方法之间存在显著的线性相关性(r = 0.80;p < 0.0001)。总之,脂肪细胞比容在区分有无脂肪吸收不良的患者方面令人满意。它是一种简单、快速、廉价且可靠的半定量检测方法,在其他方法不实用时可以使用。