Van den Neucker A, Pestel N, Tran T M, Forget P P, Veeze H J, Bouquet J, Sinaasappel M
Department of Paediatrics, University Hospital Maastricht, The Netherlands.
Acta Paediatr. 1997 May;86(5):466-9. doi: 10.1111/j.1651-2227.1997.tb08914.x.
Malabsorption of fat is an important gastrointestinal cause of malnutrition and growth retardation in childhood. The gold standard for the evaluation of fat malabsorption is the faecal fat balance method. The acid steatocrit method has recently been introduced as a simple method to evaluate faecal fat. The present study was aimed at evaluating the acid steatocrit in clinical practice. Faecal fat excretion and acid steatocrit results were determined in 42 children, half with and half without fat malabsorption. Acid steatocrit results correlated significantly with both faecal fat excretion (p < 0.01) and faecal fat concentration (p < 0.001). Sensitivity and specificity of the acid steatocrit for the diagnosis of malabsorption were 90% and 100%, respectively. We consider the acid steatocrit method useful for the screening and monitoring of patients with steatorrhoea.
脂肪吸收不良是儿童营养不良和生长发育迟缓的一个重要胃肠道病因。评估脂肪吸收不良的金标准是粪便脂肪平衡法。酸脂肪比容法最近被作为一种评估粪便脂肪的简便方法引入。本研究旨在评估临床实践中的酸脂肪比容。测定了42名儿童的粪便脂肪排泄和酸脂肪比容结果,其中一半有脂肪吸收不良,一半没有。酸脂肪比容结果与粪便脂肪排泄(p < 0.01)和粪便脂肪浓度(p < 0.001)均显著相关。酸脂肪比容诊断吸收不良的敏感性和特异性分别为90%和100%。我们认为酸脂肪比容法对脂肪泻患者的筛查和监测有用。