Bass E B, Steinberg E P, Pitt H A, Griffiths R I, Lillemoe K D, Saba G P, Johns C
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Med Decis Making. 1994 Oct-Dec;14(4):307-14. doi: 10.1177/0272989X9401400401.
To estimate patient preferences for gallstone-related treatments and outcomes, and assess how preferences vary by patient characteristics and scaling technique, the authors randomly assigned 40 patients without gallstones to interviews based on a rating scale (n = 22) and a standard gamble (n = 18). The patients assigned preference values (possible values 0 to 1) to open cholecystectomy (mean 0.45 by rating scale, 0.78 by standard gamble), laparoscopic cholecystectomy (0.71, 0.91), extracorporeal shock-wave lithotripsy (0.77, 0.89), acute cholecystitis (0.36, 0.77), lifetime biliary colic (0.41, 0.71), postcholecystectomy syndrome (0.43, 0.79), asymptomatic stone necessitating treatment with bile acids (0.76, 0.96), and surgical scar (0.79, 0.998). Preferences varied little by age, gender, or race. Standard gamble values were highly correlated with, but significantly greater than, rating scale values. The authors conclude that patients' preferences for gallstone-related conditions generally are significantly less than one, and differ markedly by the scaling technique used to derive them. These results should be considered when patient preferences are incorporated into analyses of gallstone treatments.
为了评估患者对胆结石相关治疗及结果的偏好,并评估偏好如何因患者特征和评分方法而异,作者将40名无胆结石患者随机分为两组进行访谈,一组采用评分量表(n = 22),另一组采用标准博弈法(n = 18)。患者为开腹胆囊切除术(评分量表法均值为0.45,标准博弈法为0.78)、腹腔镜胆囊切除术(0.71,0.91)、体外冲击波碎石术(0.77,0.89)、急性胆囊炎(0.36,0.77)、终身胆绞痛(0.41,0.71)、胆囊切除术后综合征(0.43,0.79)、无症状结石需用胆汁酸治疗(0.76,0.96)和手术疤痕(0.79,0.998)赋予偏好值(可能值为0至1)。偏好随年龄、性别或种族的变化不大。标准博弈法得出的值与评分量表法得出的值高度相关,但显著大于后者。作者得出结论,患者对胆结石相关情况的偏好通常显著小于1,且因用于得出偏好的评分方法不同而有明显差异。在将患者偏好纳入胆结石治疗分析时应考虑这些结果。