Seedat Y K, Mayet F G, Gouws E
Department of Medicine, University of Natal, Durban.
S Afr Med J. 1994 May;84(5):257-62.
Coronary heart disease (CHD) is the leading cause of death among the white and Indian populations of Durban. This was a community-based study of the white population of Durban, which is predominantly English-speaking. There were 396 subjects (194 men, 202 women) aged 15-69 years. A history of CHD was present in 9.3% of the subjects. The important risk factors were hypercholesterolaemia, hypertension and smoking. The minor risk factors were obesity, hypertriglyceridaemia, hyperuricaemia, a sedentary occupation and a history of CHD in the immediate family. Electrocardiograph abnormalities denoting CHD were present in 17% of subjects. A study of the major risk factors showed that 35.1% (age and sex adjusted) had at least one major risk factor at the higher level (level A) and 33.8% (age and sex adjusted) at the lower risk levels (level B). When the combination of risk factors was taken into account, 15.2% and 28% had two major risk factors, one each at levels A and B respectively. On average the percentage of men and women with one risk factor or more increased with age. A protective high-density lipoprotein/total cholesterol ratio > or = 20% was present in 53.5% of the respondents. Because of the severe nature of CHD, an intensive programme for the primary prevention of CHD risk factors should be instituted.
