Pon R T, Buck G A, Niece R L, Robertson M, Smith A J, Spicer E
University Core DNA Services, University of Calgary, AB, Canada.
Biotechniques. 1994 Sep;17(3):526-34.
Core facility services related to DNA synthesis and sequencing were surveyed by the Association of Biomolecular Resource Facilities. Responses from 85 facilities offering DNA synthesis and 37 facilities offering DNA sequencing were obtained. Data on instrumentation, volume, number of users, cost, methodology and a number of other criteria were obtained. The volume of work performed by these centralized core facilities was quite substantial (combined synthesis output of 4 million bases per year and a combined sequencing output of 35 million bases per year). The large number of users supported by these facilities and the high sample throughput make these core resource facilities good indicators of technological trends.
生物分子资源设施协会对与DNA合成和测序相关的核心设施服务进行了调查。获得了85家提供DNA合成服务的设施和37家提供DNA测序服务的设施的回复。收集了有关仪器设备、工作量、用户数量、成本、方法以及其他一些标准的数据。这些集中式核心设施所开展的工作量相当可观（每年的合成总量为400万个碱基，每年的测序总量为3500万个碱基）。这些设施所支持的大量用户以及高样本通量使这些核心资源设施成为技术趋势的良好指标。
