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后来发展为胰岛素依赖型糖尿病的儿童的围产期决定因素。

Perinatal determinants among children who later develop IDDM.

作者信息

Bock T, Pedersen C R, Vølund A, Pallesen C S, Buschard K

机构信息

Bartholin Instituttet, Københavns Kommunehospital, Copenhagen, Denmark.

出版信息

Diabetes Care. 1994 Oct;17(10):1154-7. doi: 10.2337/diacare.17.10.1154.

DOI:10.2337/diacare.17.10.1154
PMID:7821135
Abstract

OBJECTIVE

The aim of this study was to investigate whether children who develop insulin-dependent diabetes mellitus (IDDM) differ in some aspects from a matched control group at the time of birth.

RESEARCH DESIGN AND METHODS

We studied all children who were born in Denmark during the period 1973-1977 and admitted to a Danish hospital with a diagnosis of IDDM during 1978-1989. The study was conducted by combining two nationwide registries, The National Patient Registry and The Birth Registry.

RESULTS

The criteria were fulfilled by 837 children. Data regarding the age of the parents, the number of previous pregnancies of the mother, the month of birth, and the birth weight and length of the children who developed IDDM were compared with the data of an age- and sex-matched control group of 837 children without IDDM. We did not detect any significant differences between the two groups with respect to the parameters studied.

CONCLUSIONS

No differences in perinatal determinants could be demonstrated among Danish children who develop IDDM compared with children without diabetes.

摘要

目的

本研究旨在调查患胰岛素依赖型糖尿病(IDDM)的儿童在出生时是否在某些方面与匹配的对照组存在差异。

研究设计与方法

我们研究了1973年至1977年期间在丹麦出生、并于1978年至1989年期间因IDDM诊断而入住丹麦医院的所有儿童。该研究通过合并两个全国性登记处,即国家患者登记处和出生登记处来进行。

结果

837名儿童符合标准。将患IDDM儿童的父母年龄、母亲既往怀孕次数、出生月份以及出生体重和身长数据与837名无IDDM的年龄和性别匹配的对照组儿童的数据进行了比较。在研究的参数方面,我们未发现两组之间存在任何显著差异。

结论

与无糖尿病的儿童相比,患IDDM的丹麦儿童在围产期决定因素方面未显示出差异。

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