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在肥胖率较低的印度南部老年人群中,非胰岛素依赖型糖尿病(NIDDM)和糖耐量受损(IGT)的高患病率。

High prevalence of NIDDM and IGT in an elderly south Indian population with low rates of obesity.

作者信息

Ramachandran A, Snehalatha C, Shyamala P, Vijay V, Viswanathan M

机构信息

Diabetes Research Centre, Madras, India.

出版信息

Diabetes Care. 1994 Oct;17(10):1190-2. doi: 10.2337/diacare.17.10.1190.

Abstract

OBJECTIVE--To assess the prevalence of diabetes and impaired glucose tolerance (IGT) in the urban and rural elderly population in south India. RESEARCH DESIGN AND METHODS--Urban and rural populations > or = 60 years of age and representative of the areas (873 urban and 588 rural subjects) were screened for diabetes and IGT using fasting and 2-h postglucose capillary blood glucose measurements. RESULTS--In the urban area, 211 (23.7%) had diabetes, and 101 (12.4%) had IGT. In the rural area, 56 (9.9%) had diabetes, and 82 (14.9%) had IGT. The ratio of newly diagnosed to known diabetes was 1:3 in the urban and 1:1 in the rural areas. Positive family history of diabetes, body mass index (BMI), subscapular-to-triceps ratio, and waist-to-hip ratio were significantly associated with diabetes in the urban population. Only age and BMI showed significant association with diabetes in the elderly rural population. None of the tested parameters, except age in the urban subjects, showed association with IGT. CONCLUSIONS--This study highlights the high prevalence of glucose intolerance in elderly south Indians having low mean BMI (mean +/- SD; urban 21.7 +/- 4.6, rural 17.9 +/- 3.3 kg/m2). Although there was a twofold higher prevalence of diabetes in the urban area, the occurrence of IGT was similar in urban and rural populations.

摘要

目的——评估印度南部城乡老年人群中糖尿病和糖耐量受损(IGT)的患病率。研究设计与方法——对年龄≥60岁、具有地区代表性的城乡人群(873名城市受试者和588名农村受试者)进行糖尿病和IGT筛查,采用空腹及葡萄糖负荷后2小时毛细血管血糖测量。结果——在城市地区,211人(23.7%)患有糖尿病,101人(12.4%)患有IGT。在农村地区,56人(9.9%)患有糖尿病,82人(14.9%)患有IGT。城市中新诊断糖尿病与已知糖尿病的比例为1:3,农村为1:1。糖尿病家族史阳性、体重指数(BMI)、肩胛下与三头肌比值以及腰臀比在城市人群中与糖尿病显著相关。在农村老年人群中,只有年龄和BMI与糖尿病显著相关。除城市受试者中的年龄外,所检测的参数均与IGT无关联。结论——本研究凸显了平均BMI较低(均值±标准差;城市21.7±4.6,农村17.9±3.3kg/m2)的印度南部老年人群中糖耐量不耐受的高患病率。尽管城市地区糖尿病患病率高出两倍,但城市和农村人群中IGT的发生率相似。

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