苏塞克斯郡多发性硬化症患病率调查。
A prevalence survey of multiple sclerosis in Sussex.
作者信息
Rice-Oxley M, Williams E S, Rees J E
机构信息
Department of Neurology, Brighton Health Care, Royal Sussex County Hospital, UK.
出版信息
J Neurol Neurosurg Psychiatry. 1995 Jan;58(1):27-30. doi: 10.1136/jnnp.58.1.27.
Abstract
A first survey of the Brighton and Mid-Downs health districts in Sussex showed a prevalence of multiple sclerosis of 111 per 100,000 (95% confidence interval (95% CI) 103-120) in a population of 596,594 on prevalence day, 1 July 1991. Cases were notified by multiple sources and to maximise case notification patients were not contacted. Cases were classified by hospital and family practitioner notes. The Poser criteria were used for classification. These criteria are precise and exclude cases of isolated spinal cord syndrome. The Allison and Millar criteria used in the surveys in Scotland may lack specificity and it is concluded that the high prevalence of multiple sclerosis in Scotland needs to be reassessed with the more precise criteria. Until this is done, the latitude effect within the United Kingdom remains not proved.
摘要
对苏塞克斯郡布莱顿和中唐斯健康区的首次调查显示，在1991年7月1日患病率调查日的596,594人口中，多发性硬化症的患病率为每10万人中有111例（95%置信区间（95%CI）为103 - 120）。病例由多个来源报告，为了最大限度地报告病例，未与患者联系。病例根据医院和家庭医生记录进行分类。采用波泽标准进行分类。这些标准精确，排除了孤立性脊髓综合征病例。苏格兰调查中使用的艾利森和米勒标准可能缺乏特异性，得出的结论是，需要用更精确的标准重新评估苏格兰多发性硬化症的高患病率。在此之前，英国境内的纬度效应仍未得到证实。
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