Reichelt K L, Lindback T, Scott H
Department of Pediatric Research, National Hospital, Rikshospitalet, Oslo, Norway.
Acta Paediatr Jpn. 1994 Oct;36(5):489-92. doi: 10.1111/j.1442-200x.1994.tb03231.x.
An increased level of immunoglobulin A (IgA) antibodies to food antigens has been found in Down syndrome. Biopsy did not show any anomaly of the gut. Increased IgA levels against specific proteins reflect increased transmucosal transport of antigens. The antigens presented may be immunogenic peptides or intact antigens. In this paper, we wished to exclude an institutional cause such as infections and also age differences.
在唐氏综合征患者中发现，其针对食物抗原的免疫球蛋白A（IgA）抗体水平有所升高。活检未显示肠道有任何异常。针对特定蛋白质的IgA水平升高反映了抗原经黏膜转运增加。所呈现的抗原可能是免疫原性肽或完整抗原。在本文中，我们希望排除诸如感染等机构性原因以及年龄差异。
