Keyak J H, Lee I Y, Skinner H B
Rehabilitation Research and Development Service, Department of Veterans Affairs Medical Center, San Francisco, California.
J Biomed Mater Res. 1994 Nov;28(11):1329-36. doi: 10.1002/jbm.820281111.
To compare the numerous modulus-density and strength-density relations that have been found for human trabecular bone from the proximal tibia, correlations between various measures of density were sought. Hydrated and dry apparent density, ash density, and density from quantitative computed tomography (QCT) were determined for cubic trabecular specimens taken from the proximal portion of human tibiae, and correlations between these measures were found (r > 0.99, P < .001). Orthogonal moduli and strengths of the specimens were measured mechanically, and were significantly correlated with ash density according to power relations (r > or = 0.85, P < .001). The strong correlation between density from QCT and ash density indicates that these measures can be used with nearly equal precision in estimating modulus and strength of tibial trabecular bone. Equations between mechanical properties and density reported in previous studies were converted to use a common density measure and, after considering the effects of specimen size, were in general agreement with results of the present study.
为比较已发现的来自胫骨近端的人小梁骨的众多模量 - 密度和强度 - 密度关系，研究了各种密度测量值之间的相关性。对取自人胫骨近端的立方小梁标本测定了湿表观密度、干表观密度、灰密度以及定量计算机断层扫描（QCT）密度，并发现这些测量值之间存在相关性（r > 0.99，P <.001）。通过机械方法测量了标本的正交模量和强度，根据幂关系，它们与灰密度显著相关（r ≥ 0.85，P <.001）。QCT密度与灰密度之间的强相关性表明，在估计胫骨小梁骨的模量和强度时，这些测量方法可以以几乎相同的精度使用。将先前研究中报道的力学性能与密度之间的方程转换为使用共同的密度测量值，并在考虑标本尺寸的影响后，总体上与本研究结果一致。
