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Urotest AB抗菌物质检测试验的评估

Evaluation of the Urotest AB antibacterial substance detection test.

作者信息

Blondeau J M, Yaschuk Y, Galenzoski D, Hrabok D, Isaacson M, Lee L, Link H, Walshaw L

机构信息

Division of Microbiology, St Paul's (Grey Nuns') Hospital, Saskatoon, Saskatchewan, Canada.

出版信息

J Clin Pathol. 1994 Nov;47(11):1047-8. doi: 10.1136/jcp.47.11.1047.

DOI:10.1136/jcp.47.11.1047
PMID:7829684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC503073/
Abstract

The Urotest AB was used to detect antimicrobial substances in urine samples. Of 1022 urine specimens evaluated, Urotest AB detected inhibitors in 38.9%. Of 159 urine specimens from patients thought to be taking an antibiotic, inhibitors were detected in 80.5%. This test may help to explain culture negative urine samples from symptomatic patients, and could help elucidate treatment failures and the epidemiology of antibiotic resistance.

摘要

使用Urotest AB检测尿液样本中的抗菌物质。在评估的1022份尿液标本中,Urotest AB检测出抑制剂的比例为38.9%。在159份被认为正在服用抗生素的患者的尿液标本中,检测出抑制剂的比例为80.5%。该检测可能有助于解释有症状患者的尿培养阴性样本,并有助于阐明治疗失败及抗生素耐药性的流行病学情况。

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1
Evaluation of the Urotest AB antibacterial substance detection test.Urotest AB抗菌物质检测试验的评估
J Clin Pathol. 1994 Nov;47(11):1047-8. doi: 10.1136/jcp.47.11.1047.
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Microbiologic assay for detection of antimicrobial agents in urine.尿液中抗菌药物检测的微生物学测定法。
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本文引用的文献

1
Cranberry juice and the antibacterial action of hippuric acid.蔓越莓汁与马尿酸的抗菌作用。
J Lab Clin Med. 1959 Dec;54:881-8.
2
Inhibitory substances in urine: an addition to the routine screen.尿液中的抑制物质:常规筛查的补充项目
Med Lab Sci. 1982 Oct;39(4):377-81.
3
Antibacterial activity of human urine.人尿液的抗菌活性。
J Clin Invest. 1968 Oct;47(10):2374-90. doi: 10.1172/JCI105921.
4
Simple microbiological method for the identification of antimicrobial agents prescribed in general practice.用于识别普通医疗实践中所开抗菌药物的简易微生物学方法。
J Clin Microbiol. 1985 May;21(5):741-4. doi: 10.1128/jcm.21.5.741-744.1985.
5
[Detection of bacterial inhibitors in urine and their preliminary identification].[尿液中细菌抑制剂的检测及其初步鉴定]
Z Gesamte Hyg. 1977;23(6):383-6.