The identification of a Caenorhabditis elegans homolog of p34cdc2 kinase.
作者信息
Mori H, Palmer R E, Sternberg P W
机构信息
Howard Hughes Medical Institute, California Institute of Technology, Pasadena 91125.
出版信息
Mol Gen Genet. 1994 Dec 15;245(6):781-6. doi: 10.1007/BF00297285.
PMID:7830726
Abstract
We have identified a Caenorhabditis elegans homolog of p34cdc2 kinase. The C. elegans homolog, ncc-1, is approximately 60% identical to p34cdc2 of Homo sapiens. When expressed from a constitutive yeast promoter, ncc-1 is capable of complementing a conditional lethal mutation in the CDC28 gene of Saccharomyces cerevisiae, indicating that this C. elegans homolog can properly regulate the cell cycle.
摘要
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