沙眼衣原体抗体简易血清学检测
Simplified serological test for antibodies to Chlamydia trachomatis.
作者信息
Thomas B J, Reeve P, Oriel J D
出版信息
J Clin Microbiol. 1976 Jul;4(1):6-10. doi: 10.1128/jcm.4.1.6-10.1976.
Abstract
Three-hundred sixty sera from unselected patients attending two London venereal disease clinics were examined by a microimmunofluorescence test. Eleven egg-grown serotypes of Chlamydia trachomatis and the so-called "fast" strain SA2(f) were used as antigens. Of the 360 sera tested, 119 (33%) reacted to a titer of 1:16 or above with at least one antigen. Of these positive sera, over 50% cross-reacted with all 12 serotypes, and 95.5% reacted with SA2(f) in addition to other antigenic types. It is suggested that SA2(f) could be used as a single antigen for preliminary screening of a large number of sera for the presence or absence of chlamydial antibody.
摘要
采用微量免疫荧光试验对来自伦敦两家性病诊所未经挑选的360份患者血清进行检测。使用11种沙眼衣原体鸡胚培养血清型以及所谓的“快速”菌株SA2(f)作为抗原。在检测的360份血清中，119份（33%）与至少一种抗原反应，滴度达到1:16或更高。在这些阳性血清中，超过50%与所有12种血清型发生交叉反应，95.5%除了与其他抗原类型反应外，还与SA2(f)反应。建议SA2(f)可作为单一抗原用于对大量血清进行初步筛查，以检测衣原体抗体的有无。
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