Ashraf S S, Shaukat N, Akhtar K, Love H, Shaw J, Rowlands D J, Keenan D
Department of Cardiothoracic Surgery, Manchester Royal Infirmary.
Br Heart J. 1994 Oct;72(4):321-6. doi: 10.1136/hrt.72.4.321.
To compare differences in early mortality and morbidity in patients receiving a single internal mammary artery graft (SIMA) with those receiving bilateral internal mammary artery grafts (BIMA) with a free right internal mammary artery (RIMA).
Retrospective analysis of 150 patients undergoing BIMA grafting between 1989-1992 who were carefully matched with 150 patients undergoing SIMA grafting between 1987-1992 for known cardiovascular risk factors, extent of coronary disease, left ventricular function, and number of coronary grafts. Operative variables noted included aortic cross clamp time and bypass time. Postoperative cardiac, respiratory, and wound complications were also noted.
Operative mortality was 2% in the SIMA group and 1.3% in the BIMA group (NS). Other than the prevalence of ventricular arrhythmias (P = 0.025), which were more common in the BIMA group, there were no significant differences between the two groups in terms of postoperative morbidity. At median (interquartile range) follow up of 27.94(0.86) and 23.94(0.74) months for the SIMA and BIMA groups respectively there were no deaths. 87% of the SIMA group and 91% of the BIMA group were free of symptoms at follow up.
The earlier fears regarding increased early mortality and morbidity after BIMA surgery were not confirmed by this study. All patients receiving both mammary arteries had a free rather than pedicle right internal mammary graft. The early mortality and morbidity reported here compares favourably with previous reports on the use of a pedicle graft.
比较接受单支内乳动脉移植(SIMA)的患者与接受双侧内乳动脉移植(BIMA)并游离右侧内乳动脉(RIMA)的患者在早期死亡率和发病率方面的差异。
对1989年至1992年间接受BIMA移植的150例患者进行回顾性分析,这些患者与1987年至1992年间接受SIMA移植的150例患者在已知心血管危险因素、冠心病程度、左心室功能和冠状动脉移植数量方面进行了仔细匹配。记录的手术变量包括主动脉交叉钳夹时间和体外循环时间。还记录了术后心脏、呼吸和伤口并发症。
SIMA组手术死亡率为2%,BIMA组为1.3%(无显著差异)。除室性心律失常的发生率(P = 0.025)在BIMA组中更高外,两组在术后发病率方面无显著差异。SIMA组和BIMA组的中位(四分位间距)随访时间分别为27.94(0.86)个月和23.94(0.74)个月,均无死亡病例。随访时,SIMA组87%的患者和BIMA组91%的患者无症状。
本研究未证实先前关于BIMA手术后早期死亡率和发病率增加的担忧。所有接受双侧内乳动脉移植的患者均采用游离而非带蒂的右侧内乳动脉移植。此处报告的早期死亡率和发病率与先前关于使用带蒂移植的报告相比更有利。