Murshid W R, Siquiera E, Rahm B, Kanaan I
Department of Surgery, King Khalid University Hospital, Riyadh, Saudi Arabia.
Childs Nerv Syst. 1994 Sep;10(7):430-2. doi: 10.1007/BF00303607.
Thirty-four patients with brain tumors were diagnosed and treated during the first 2 years of life, representing 8% of the 273 children treated for primary brain tumors from 1981 to 1990 inclusive. Large head circumference, vomiting, and altered level of consciousness were the chief findings at the time of presentation. Overall, the tumors were located mainly supratentorially; in patients in the 1st year of life they were equally distributed above and below the tentorium, while two-thirds of the patients presenting in the 2nd year of life had supratentorial tumors. The most common histological types were astrocytomas and medulloblastomas. Treatment methods were ventricular peritoneal shunt, craniotomy with total or partial removal of the tumor, adjuvant radiotherapy, and in a few cases chemotherapy. The 2-month mortality rate was 5.9%. The follow-up period ranged from 3 to 50 months.
34例脑肿瘤患者在出生后头2年内被诊断并接受治疗，占1981年至1990年（含）期间接受原发性脑肿瘤治疗的273名儿童的8%。就诊时的主要表现为头围增大、呕吐和意识水平改变。总体而言，肿瘤主要位于幕上；1岁儿童患者的肿瘤在幕上和幕下分布均等，而2岁儿童患者中三分之二有幕上肿瘤。最常见的组织学类型是星形细胞瘤和髓母细胞瘤。治疗方法包括脑室腹腔分流术、开颅肿瘤全切或部分切除术、辅助放疗，少数病例采用化疗。2个月死亡率为5.9%。随访期为3至50个月。
