Staley A L, Rinehart K L
Roger Adams Laboratory, University of Illinois, Urbana 61801.
J Antibiot (Tokyo). 1994 Dec;47(12):1425-33. doi: 10.7164/antibiotics.47.1425.
Three new tetrahydroanthracene antibiotics have been isolated from modified culture broths of Streptomyces spectabilis. The new compounds, spectomycins A1, A2 and B1, exist as monomeric (C20H20O7, A1; C19H18O7, A2) and as symmetrical dimeric (C38H34O14; B1) forms. Only spectomycin B1 has moderate activity against Gram-positive microorganisms. We report here the structure elucidation and biosynthetic origin of these compounds.
