Cohen E, Navaline H, Metzger D
University of Pennsylvania/Veterans Administration Medical Center, Center for Studies of Addiction, Philadelphia 19104.
J Psychoactive Drugs. 1994 Jul-Sep;26(3):233-41. doi: 10.1080/02791072.1994.10472436.
High rates of unprotected sexual behaviors and the exchange of sex for crack have been reported among female crack cocaine users. This subpopulation of drug users is at significant risk for contracting and transmitting HIV and AIDS. To date, there has been no research comparing crack- and opioid-abusing women, particularly regarding their involvement in high-risk behaviors and other key background indicators for different subgroups of drug-abusing women. Sixty-one crack-abusing African-American women who recently entered an intensive outpatient treatment program were compared to 64 matched women whose primary drug of abuse was heroin. The opioid subgroup represented both those who were involved in methadone maintenance and those who were out of treatment. Higher rates of high-risk sexual behaviors were reported by the crack subgroup, including prostitution, number of sexual partners, and infrequency of condom use. As expected, i.v. drug use and high-risk behaviors associated with needle use were much higher among the opioid subgroup. Other significant differences were found between the two groups across key indicators. Individuals in the crack subgroup were younger, cared for more children, were less employable, were less likely to be married, and had more extensive lifetime substance abuse. Quantitative and qualitative background and clinical data are also presented. The nature of crack versus heroin abuse is also discussed, particularly in relation to high-risk sexual behaviors. Finally, the impact of the findings on developing appropriate treatment interventions for both groups is addressed.
据报道,女性快克可卡因使用者中存在高比例的无保护性行为以及以性换快克的情况。这一吸毒亚群体感染和传播艾滋病毒及艾滋病的风险极高。迄今为止,尚未有研究对滥用快克和阿片类药物的女性进行比较,尤其是在她们参与高危行为以及吸毒女性不同亚组的其他关键背景指标方面。将61名最近进入强化门诊治疗项目的滥用快克的非裔美国女性与64名匹配的主要滥用药物为海洛因的女性进行了比较。阿片类药物亚组包括参与美沙酮维持治疗的人和未接受治疗的人。快克亚组报告的高危性行为发生率更高,包括卖淫、性伴侣数量以及避孕套使用频率低。不出所料,静脉注射吸毒以及与针头使用相关的高危行为在阿片类药物亚组中要高得多。在关键指标方面,两组之间还发现了其他显著差异。快克亚组中的个体更年轻、照顾的孩子更多、就业能力更低、结婚可能性更小,并且有更广泛的终生药物滥用情况。还呈现了定量和定性的背景及临床数据。还讨论了快克滥用与海洛因滥用的性质,特别是与高危性行为的关系。最后,阐述了研究结果对为两组制定适当治疗干预措施的影响。